The "old" WNV shots are given twice, 4-6 week apart, if the horse has never been vaccinated for WNV before.
We started out using the original Fort Dodge vaccine--gave it to all our pregnant mares with no problems. The one year we did use the Merial vaccine and gave that to our bred mares as well--again, with no problems. It was only later that I was told that it shouldn't be given to pregnant mares because it is a modified live virus vaccine. I mentioned this to our vet, and she said oh, she hadn't even thought about that. (Obviously, neither had I!! ) In any case, we had no problems from it, at least not in terms of the pregnant mares. We did have some major neck lumps from giving the Merial--they took ages to go away--and because of that we went back to the FD vaccine. However, the past two years & again this year we switched to the FD combo shot which covers E/W/T + WNV--again, that's been given to the bred mares with no problems.
The FD combo shot is actually the only thing that is available at most clinics here this year. One clinic (not any of the local ones) did have the Merial, and my vet said she would order in the Prevenile if we wanted. We chose to go with the combo shot again. Because our mosquito season is relatively short, we only give the vaccine once a year, in early to mid May. By the time it's effectiveness starts to drop off, our mosquito season is pretty much over.
But, to answer your question--I believe the Prevenile is also a modified live virus type and so probably is not labelled for pregnant mares (I haven't seen the vaccine's label or product insert so can't say for sure what it says).