Last year one of the foals that I sold to a young lady injured one of his back legs. Her vet prescribed butte to be given twice a day. She ended up losing the colt from an overdose of butte. She was heartbroken and a beautiful weanling colt died as a result. The vets in our area tend to prescribe way too much for the size of the horse. This is one of the reason why I wonder how a person can raise minis without the expertise of the Forum members.
I have copied this from Dr. Pam and I'm sure she won't mind me sharing it.
Everytime I sell a mini, I include this article on butte.
Dr. Pam Posted: Feb 15 2004, 09:29 AM
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Just had several questions on this again, and it's worth reminding people periodically, so here's part of my reply:
Bute is incredibly toxic to minis, and for some reason a lot of vets out there don't realize this. Not only is there a very narrow safety margin, i.e. you have to be very accurate at dosing them, but there are minis who will have problems even at the correct dose. It should be given at 1mg per pound body weight, which means most minis will get 150 mg to 250 mg--1/4 tablet or less. A lot of vets seem to think the average mini weighs 500 pounds and have owners give 1/2 tablet twice daily. ARGGGG!!!
Bute toxicity can cause severe gastric and intestinal ulceration, to the point of perforation and death (in as little as 5-7 days), kidney and liver damage, bone marrow suppression, and lowered blood protein levels.
That said, I have used bute on selected minis for laminities, but at a low dose and for short periods of time. For almost everything else I use Banamine (which can also cause problems if dosed too high or too long, but has a wider safety margin)
From Plumb's Veterinary Drug Handbook:
QUOTE
Adverse effects: Horses: oral and GI erosions and ulcers, hypoalbuminemia, diarrhea, anorexia, and renal (KIDNEY) effects.
QUOTE
Cautious use in both foals and ponies is recommended because of increased incidences of hypoproteinemia (LOW BLOOD PROTEIN LEVELS)and GI ulceration. Foals with a heavy parasite burden or that are undernourished may be more susceptible to development of adverse effects.
Phenylbutazone may cause decreased renal blood flow and sodium and water retention, and should be used cautiously in animals with preexisting renal disease or CHF (CONGESTIVE HEART FAILURE).