Well since you say the horse has to carry the splash or frame gene to have blues eyes, I would assume that this also is true in the big horses, right? Now tell me how a Quarter Horse from well know bloodlines was born with two very blue eyes (the horse was a liver chestnut so his eyes really stood out) and 4 high white socks. His mother was a solid chestnut with a star and if I am correct his sire was a dark chestnut with some roaning (but not 100% sure). Quarter Horses are not suppose to have pinto or overo genes so where did this colt get his blue eyes? This was years ago (about 28 years) when they pulled papers for to much white in the Quarter Horse association.
Just curious because I still wonder about this.